Good evening, Ohio. We're wrapping up the day for you with the most important stories you need to know and your weather outlook.

A cold front tonight will bring in even cooler air for Friday and another round of snow showers. Snow accumulations will be mainly light (1-3 inches) along and north of I-70 from the morning through the early afternoon. Highs will be below normal in the lower to upper 30s.

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1. Flu vaccine clinical trial underway nationwide, including in Ohio

Phase 3 of a mRNA flu vaccine clinical trial is underway across the country, including here in Ohio, to see if mRNA technology used to create COVID-19 vaccines could provide better protection against other viruses, including the flu 

2. 'We must move boldly into the future': Pelosi will not seek another term as House Democratic leader

One day after Republicans were projected to retake the House majority, Speaker Nancy Pelosi announced that she will not seek another term as House Democratic leader, a role she has held for nearly two decades.

3. Nationwide Children's Hospital sparks joy for pediatric patients

A new holiday tradition is spreading a little extra holiday cheer for pediatric patients this season. Nationwide Children's Hospital lit up several butterfly lights throughout Central Ohio. One display is right outside the hospital along Livingston Avenue.

Several butterfly-themed lights shine bright in front of Nationwide Children's Hospital. (Spectrum News 1/ Aliah Keller)

4. U.S. jobless claims fell to 222K last week

The U.S. job market remains healthy as fewer Americans applied for unemployment benefits last week, despite the Federal Reserve's rapid interest rate hikes this year intended to bring down inflation and tighten the labor market.

5. Familiar foes face off in OHSAA Game of the Week in Region 1

The 2022 Ohio High School Athletic Association football postseason has reached an interesting nexus. For the 56 teams still playing, they are officially on a playoff run, winning three straight games.

On Friday, Nov. 18

• ​COP27 concludes in Egypt as the global community is urged to reach a climate change deal.
  
• Vice President Harris attends the APEC Economic Leaders' Meeting.
  
• Vice President Harris and Second Gentleman Doug Emhoff​ meet the Thai king and queen.
  
• NATO Parliamentary Assembly Annual Session opens.
  
• Court hearing for Proud Boys members charged with seditious conspiracy for their roles in the January 6th Capitol attack.
  
• Sentencing of Theranos founder Elizabeth Holmes on wire fraud charges.
  
• Adele begins her postponed Las Vegas residency.
  
• 'Christmas Spectacular Starring the Radio City Rockettes' begins.