Louisville (4-0, 2-0 Atlantic Coast Conference) at North Carolina State (3-1, 1-0), Friday, 7 p.m. ET (ESPN)

Line: Louisville by 3 1/2, according to FanDuel Sportsbook.

Series record: Louisville leads 8-4.

WHAT’S AT STAKE?

Both teams are unbeaten in ACC play, with Louisville chasing its first 5-0 start since 2013. N.C. State’s only loss came to highly ranked Notre Dame and is playing the second of two straight Friday games against league foes after winning last week at Virginia in its league opener.

KEY MATCHUP

Louisville’s offense vs. N.C. State’s defense. The Cardinals are off to a fast start under first-year coach Jeff Brohm, ranking fifth in the Bowl Subdivision ranks in total offense (542.0 yards per game) and ninth in scoring (43.0). Defense has been a multi-year strength for the Wolfpack, who allowed 326 yards per game through the first four games along with ranking tied for 14th nationally in third-down defense (30% conversion rate).

PLAYERS TO WATCH

Louisville: RB Jawhar Jordan and WR Jamari Thrash. They’ve formed a formidable big-play duo. Jordan ranks eighth nationally with 119.5 yards rushing per game and averages 9.6 yards per carry, while Thrash ranks 19th with 100 yards per contest and has five TDs.

N.C. State: WR KC Concepcion. The freshman had a big game at Virginia with six catches for 116 yards and two touchdowns. It’s a much-needed sign of development for a team still hunting for go-to threats at wideout.

FACTS & FIGURES

N.C. State hasn’t lost its first ACC home game since falling to Louisville in 2015. ... Wolfpack coach Dave Doeren is two wins from tying the program record for coaching victories. ... Louisville is playing its second Friday night game this season four weeks after rallying past Georgia Tech 39-34. The Cardinals are 16-13 all-time on Friday night. ... Louisville QB Jack Plummer threw for a career-high five TDs among six scores overall against Boston College last week, completing 18 of 21 for 388 yards. That includes 15 straight completions during one stretch that marked the fourth-longest in school history. ... The Wolfpack will induct former N.C. State player and Super Bowl-winning coach Bill Cowher to its Ring of Honor during the game.