CINCINNATI (AP) — A gunman opened fire Thursday morning in a building in the heart of Cincinnati in an attack that left him and three other people dead, police said.

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The shooting sent people scrambling across the city's Fountain Square amid cries of "shooter!"

It happened at a 30-story building, home to the corporate headquarters for regional banker Fifth Third Bancorp and other businesses, including popular ice cream, pastry and sandwich shops. The bank building was locked down for most of the morning, and surrounding streets and sidewalks were closed off.

Police Chief Eliot Isaac said the shooter opened fire at about 9:10 a.m. at the loading dock of the Fifth Third Bank building. Isaac said the gunman then entered the bank's lobby where he exchanged gunfire with police. It was unclear if the gunman shot himself or was shot by officers.