NEW HAVEN, Ct. — Muscle soreness has developed as a typical side effect from the COVID-19 vaccines.

Now, a new Yale study — published for the American Society for Microbiology — suggests some common medication used to treat pain could lessen the effectiveness of COVID-19 vaccines.

The study was conducted primarily on mice and found NSAIDs like ibuprofen and Aleve could decrease antibody production in the body. University of Kentucky Pharmacist Frank Romanelli said side effects associated with the vaccines are largely minimal.

"You’re gonna get arm soreness after the second dose, typically. Some people may get some fever and some muscle aches. It typically lasts for 24 hours," Romanelli said.

He added that patients should be able to avoid medications if they and their doctors are concerned.

"There’s no need to rush through a lot of these side effects. Lay down, get a blanket, get a cup of coffee, rest; and typically, the next day, you’ll feel perfectly fine without the need to ingest any Tylenol or ibuprofen or aspirin."

Studies on anti-inflammatory drugs reducing antibody production have been conducted long before COVID-19 developed. Romanelli suggests talking to your doctor about medications you’re taking ahead of receiving your vaccine.